Issue 19 - Unlocking the Power of Cannabis: From Cancer Cells to Brain Health - A Medical Revolution!

BudMed Bulletin for 16/1/2025

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Discover the Game-Changer: How Cannabidiol Could Revolutionise Alcohol Use Disorder Treatment!

Reduces Cravings: CBD might help decrease the desire for alcohol by calming reactions to alcohol and stress triggers. Balances Brain Functions: It can normalise brain functions that are thrown off by alcohol use, potentially reducing the chance of relapse. Improves Mood and Sleep: CBD can enhance mood and sleep quality, which are often disturbed in those with alcohol use disorder, making relapse less likely. Safe with Fewer Side Effects: Compared to other addiction treatments, CBD has fewer and less severe side effects, making it easier for people to stick with their treatment plan. Protects Organs: CBD's anti-inflammatory and antioxidant effects could protect your liver and brain from damage caused by alcohol. Source

Cannabis for Cirrhosis: Study Finds It Might Slash Healthcare Use and Boost Recovery!

"Conclusion: Cannabis use in patients with cirrhosis resulted in mixed outcomes regarding hospital admissions with hepatic decompensation. A trend towards decreased hospital utilisation and mortality was noted in cannabis users after legalisation." Source

Surprising Recovery: Patients with Cannabis in System Show Better TBI (Traumatic Brain Injury) Outcomes Despite More Severe Injuries

Recovery and Discharge: Patients who tested positive for cannabis: Were more likely to be discharged directly home rather than to another care facility. Had better outcomes on the modified Rankin Scale (mRS) at discharge, which measures disability and dependence in daily activities. Had shorter hospital stays. Statistical Analysis: After adjusting for various factors, the study found that having cannabis in your system was generally associated with these better outcomes in a way that was statistically significant, meaning it's unlikely these results happened by chance. Source

Revolutionise Your Health: CBD's Secret Weapon Against Anxiety, Depression & More Revealed!

Therapeutic Effects: CBD exerts a range of therapeutic benefits through its interactions with serotonin receptors. Anxiolytic Properties: CBD reduces anxiety by interacting with serotonin receptors. Antidepressant Effects: Its antidepressant actions are facilitated through this same receptor pathway. Antipsychotic Benefits: CBD shows potential in managing symptoms of psychosis through serotonin receptor interaction. Anti-degenerative and Neuroprotective: CBD's ability to protect neurons and combat neurodegeneration is linked to its effects on serotonin receptors. Anti-epileptic: The compound's use in managing epilepsy is partly due to its influence on serotonin pathways. Anti-addictive: CBD's potential in reducing addiction is mediated by its interaction with these receptors. Source

CBN & CBG: The Cannabis Compounds That Could Crush Leukemia? New Study Reveals Shocking Results!

"Taken together, CBG and CBN exhibited suppressive, cell death-inducing effects on leukemia cells." Source

"Cannabidiol Targets Colorectal Cancer Cells via Cannabinoid Receptor 2 [CB2]"

CB2 Receptor Misconception: Previously, the CB2 receptor was thought to be exclusively expressed in immune cells, thus not considered a target for colorectal cancer (CRC) treatment.

CB2 Receptor Action: The study found that CBD primarily interacts with CRC cells via the CB2 receptor.

Biological Effects of CBD: ER Stress: CBD was shown to induce endoplasmic reticulum (ER) stress in CRC cells. By inducing ER stress, CBD could push CRC cells towards apoptosis, or programmed cell death. Apoptosis: It promotes programmed cell death. Proliferation Inhibition: CBD inhibits the growth of CRC cells. Migration and Invasion: It also reduces the cells' ability to migrate and invade, which are crucial in cancer spread. Source

Discover the Game-Changer: Cannabis Compounds Show Promise in Battling Lung Disease

Several types of lung and immune cells were found to have receptors for cannabis compounds. Using certain cannabis substances slowed down the growth of both lung tissue and immune cells after 5 days. These substances altered protein levels: Increased TGF-β1 and TNF-α, which can affect inflammation and healing. Decreased IL-8, which is involved in inflammation. The usual blockers for these receptors didn't work as expected, suggesting there might be an unconventional pathway at play. One specific cannabis compound decreased the production of collagen type I in cells from patients with idiopathic pulmonary fibrosis, which is significant in lung scarring. Source

BREAKTHROUGH: CBD Could be the Game-Changer in Vascular Health!

New research shows Cannabidiol (CBD) isn't just for relaxation - it's a powerhouse for your heart! Effective against: Atherosclerosis Stress-Induced Hypertension Diabetes-Related Vascular Disease (DRVD) Ischemia/Reperfusion Injury. Plus, it tackles damage from smoking & alcohol. Source

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Disclaimer: The content provided in this newsletter by BudMed Bulletin is for informational and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition or the use of medical cannabis.