Issue 26 - Battling Chronic Symptoms in the Covid Pandemic—Plus, CBD’s Tumour-Killing Secret Could Change Everything!

BudMed Bulletin for 06/03/2025

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Shocking Relief: 9 in 10 People Turned to Cannabis for Chronic Symptoms During COVID-19 – Here’s What They Treated!

Trouble sleeping (69.2%). Long-term pain not from cancer (49.7%). Short-term pain (46.5%). Headaches or migraines (39.0%). Muscle spasms (33.6%). Nausea or vomiting (30.6%). Boosting appetite (29.9%). Source

"Erdington tattooist took '22 tablets a day' before finding 'transformational' medicinal cannabis" 

A former tattooist who at one stage was taking 22 tablets a day to treat her endometriosis says her pain has been transformed by medical cannabis." Source

Stressed? Seizures? Addiction? New study reveals CBD’s brain-boosting powers—thanks to its secret weapon, the 5-HT1A receptor!

A big review of studies shows CBD (a compound from cannabis) has many helpful effects on the brain and nerves: It can lift your mood (like an antidepressant) It can calm anxiety It protects nerve cells It can help with serious mental health issues (like an antipsychotic) It reduces nausea and vomiting It eases certain types of pain It helps control seizures (like in epilepsy) It slows down damage to the brain and nerves It may help treat addiction These benefits partly come from how CBD works with a specific brain receptor called 5-HT1AR. Source

Enhancing THC's Therapeutic Efficacy in Inflammatory Bowel Disease

Low doses of THC, mixed with ZCZ011 or CBD, safely tackle gut inflammation and metabolism issues in IBD (inflammatory bowel disease). These combos balance key body chemicals (GLP-1 and ammonia), easing colitis and related problems like metabolism glitches and beyond-the-gut symptoms. This two-pronged attack fixes flaws in current treatments, showing cannabis-based tweaks could be a game-changer for IBD. Source

CBD’s secret weapon unveiled: How it triggers tumor cell self-destruct mode—could this be cancer’s kryptonite?

CBD mainly triggers cancer cells to self-destruct (apoptosis). It also kicks in cleanup (autophagy) and cell breakdown (necrosis) for a triple attack. Pairing CBD with standard chemo drugs could supercharge cancer-killing power. Source

Cannabis flowers vs. cancer: Explosive study uncovers their tumour-busting, inflammation-crushing potential

Cannabinoids (from cannabis) stop cancer cells from growing, spreading, and help kill them off. They boost cancer cell death by 51%–77.6%. Combining CBD, THC, and humulene (a cannabis compound) strongly fights breast cancer resistance by: Lowering proteins (PD-1/PD-L1) that shield cancer from the immune system. Reducing harmful cell stress. The combo of all three works best, hinting they team up to tackle cancer’s defences. Source

Mixing CBD with Common Chemo Drugs May Boost Effectiveness Against Tough-to-Treat Ovarian Cancer

"Integrating CBD with chemotherapy could improve cancer therapy and address drug resistance. Sequential administration of CBD and chemotherapeutic agents is more beneficial than simultaneous administration." Source

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Disclaimer: The content provided in this newsletter by BudMed Bulletin is for informational and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition or the use of medical cannabis.