Issue 57 - Cannabis Breakthroughs Unveiled: Slash Nerve Pain by 30%+, Replace Opioids, Boost Mood & Sleep, and Tame Alzheimer’s Inflammation!

BudMed Bulletin for 9 Oct 2025

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Cannabis Cuts Nerve Pain by 30%+ for 88% of Spinal Cord Injury Patients, Replaces Opioids in 47%!

How bad was the pain? On a scale of 0 to 10, participants rated their pain over the past week at an average of 6.8, which is considered moderate to severe. Did cannabis help? 88% said cannabis reduced their pain by more than 30%. 92% felt cannabis helped them cope better with their pain symptoms. Did people replace other meds with cannabis? 83% of participants used cannabis instead of their usual pain medications. The most commonly replaced meds were:Opioids (47%), like strong prescription painkillers. Gabapentinoids (43%), drugs often used for nerve pain. Over-the-counter pain meds (42%), like ibuprofen or acetaminophen. Source

Medicinal Cannabis (MC) Slashes Chronic Pain & Boosts Life Quality in Just 3 Months!

After three months of MC use: Pain intensity and its impact on daily life dropped significantly. Quality of life, general health, mood, and sleep improved noticeably. Only one mild side effect was reported. What does this mean? Early results suggest MC can help reduce pain and improve life quality, mood, and sleep for people with chronic pain. More people are using MC, and these findings show it may be effective and safe. The study suggests MC should be more accessible and less expensive to help more people. Source

Could CBD Revolutionize Alzheimer's Treatment? New Study Shows It Tames Brain Inflammation by Targeting IDO & cGAS Pathways!

Key findings: CBD lowered the activity of IDO and cGAS in the brain. This led to reduced levels of pro-inflammatory cytokines (like TNF-α, IL-1β, and IFN-γ), which are molecules that increase inflammation. CBD likely interacts with three key targets in the brain:AKT1: Controls inflammation and helps brain cells survive. TRPV1: Affects pain perception and inflammation in the brain. GPR55: Influences how immune cells in the brain are activated. Why this matters:CBD could be a new way to treat AD by targeting inflammation, either alone or combined with other treatments. The study supports the idea that chronic inflammation drives AD and that targeting the immune system could help stop this damage. Source

Women with Chronic Pain Find Relief with Cannabis Extracts! Study Shows Tailored CBD/THC Doses Ease Pain, Boost Mood, Sleep & More!

What were the results? Pain relief: Every woman reported at least some reduction in pain. Other benefits: Most saw improvements in: Thinking and focus (cognitive function). Moving around (motor abilities). Work or daily tasks (professional activities). Feeling less irritable, anxious, or sad. Less tiredness and better sleep. Life improvements: Women shared that the extracts helped their relationships and overall quality of life. Fewer medications: Many women were able to cut down or stop using other pain or mood medications. No major side effects: No one had to stop using the cannabis extracts because of bad side effects. Source

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Disclaimer: The content provided in this newsletter by BudMed Bulletin is for informational and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition or the use of medical cannabis.