BudMed Bulletin for 26 Feb 2026
In this issue:
"Moderate Cannabis Use May Protect the Aging Brain"!
US teens are using way less cannabis!
CBD + CBC combo CRUSHES chemo-resistant triple-negative breast cancer!
THC+CBD combo knocks out acute migraine pain!
THC/CBD combo beating brain tumors in trials?
Neuro Science reports: "Moderate Cannabis Use May Protect the Aging Brain"!
"New research has uncovered a surprising link between cannabis use and brain health in middle-aged and older adults.
In a large-scale study involving over 26,000 participants from the UK Biobank, researchers found that lifetime cannabis use in adults ages 40 to 77 was generally associated with larger volumes in specific brain regions and superior cognitive function."
Preserved Brain Volume: Cannabis users showed larger regional brain volumes in areas with high density of CB1 receptors, including the hippocampus, which is vital for memory and often shrinks with age and dementia.
Cognitive Boost: Participants with a history of cannabis use performed better on tests measuring learning, memory, processing speed, attention, and executive function.
Science Direct reports: US teens are using way less cannabis!
Ever used (lifetime): Dropped from about 47% in 1999 to 30% in 2023.
Recent use (past month): Dropped from about 27% in 1999 to 18% in 2023
Started very young: Dropped from about 12% in 1999 to 7% in 2023.
A report in Springer Nature found: CBD + CBC combo CRUSHES chemo-resistant triple-negative breast cancer!
The CBC + CBD combo worked much better together than either one alone → they synergistically killed or stopped the growth of doxorubicin-resistant TNBC cells (tested in flat dishes and 3D models that mimic real tumors).
The combo stopped cancer cells in the resting phase (G0/G1 arrest), preventing them from dividing and growing.
It also cut the cells' ability to invade and spread by about 55% in an invasion test.
A RCT study found: THC+CBD combo knocks out acute migraine pain!
The THC + CBD combination was clearly better than placebo:
~67% got good pain relief at 2 hours (vs ~47% with placebo)
~35% became completely pain-free at 2 hours (vs ~16% placebo)
~60% got relief from their worst symptom at 2 hours (vs ~35% placebo)
Benefits often lasted — full pain-free at 24 hours, and worst-symptom relief up to 48 hours.
This study showed: THC/CBD combo beating brain tumors in trials?
Plus, CBD slashed COVID risk!
Lab studies (test tubes and animals) and early human trials show cannabinoids can help fight several cancers, including skin melanoma and aggressive brain cancer (glioblastoma).
The first promising clinical trials combined a THC + CBD spray with the chemotherapy drug temozolomide and showed real benefits against highly invasive brain tumors.
Covid - Cannabinoids can block the virus from entering cells (by lowering ACE2 receptors), stop the virus from copying itself, prevent it from fusing with cells, and calm the dangerous inflammation it causes.
One large study of 93,565 people in Chicago found that those who had used CBD before the pandemic had a significantly lower chance of catching COVID-19.
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Disclaimer: The content provided in this newsletter by BudMed Bulletin is for informational and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition or the use of medical cannabis.
