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BudMed Bulletin for 30 Apr 2026

  • Cannabinoids significantly reduce fibromyalgia pain!

  • CBN stops 3 types of cancer cells from growing!

  • CBD cannabis powerfully boosts your body’s natural anti-inflammatory

  • CBD & THC could be game-changers for brain disorders!

This PubMed study reports: Cannabinoids significantly reduce fibromyalgia pain!

  • Cannabinoids significantly reduced pain intensity (a large drop in pain scores).

  • Pain relief worked both in the short term (under 3 months) and longer term (3 months or more).

  • Patients also reported meaningful improvements in: sleep quality, anxiety, depression, and overall quality of life.

Science Direct reports: CBN stops 3 types of cancer cells from growing!

  • CBN slowed down the growth and multiplication of all three types of cancer cells - brain, liver and breast!

  • Effect on cell sensors: CBN changed the amounts of certain “receptors” on the cancer cells (GPR18, CB2, and GPR55) that respond to cannabinoids.

  • Different pathways blocked:

  • In brain and liver cancer cells, it turned off the ERK1/2 signaling pathway (which normally tells cells to grow).

  • In breast cancer cells, it turned off the AKT signaling pathway (another key growth signal).

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A PubMed Study reports: CBD cannabis powerfully boosts your body’s natural anti-inflammatory compounds!

  • High-CBD cannabis clearly increased certain eicosanoids (fat-based signaling molecules) in the blood, especially ones called lipoxins (which help calm inflammation).

  • CBD appears to boost the body’s natural anti-inflammatory molecules through a specific pathway (15-LOX).

Springer Nature reports: CBD & THC could be game-changers for brain disorders!

  • Cannabinoids can positively influence all four stress areas:

  • Balancing oxidative stress

  • Calming or changing support cells in the brain (glia) Stabilizing brain circuits

  • Helping with protein cleanup (autophagy) and stress responses (UPR)

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Disclaimer: The content provided in this newsletter by BudMed Bulletin is for informational and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition or the use of medical cannabis.

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